PMID21704212

PMID21704212 : Effects of metformin in adolescents with polycystic ovary syndrome undertaking lifestyle therapy: a pilot randomized double-blind study.
Abstract
Our small study does not support the addition of metformin to the lifestyle of adolescents. Although there are favorable trends toward hyperandrogenism with metformin, these must be balanced against the increased rate of gastrointestinal side effects. However, other treatments were associated with an improved quality of life.
Structured Findings
Metformin and Control had no significant difference on Quality of life
Structured Markup
Intervention Comparator Outcome Label
Metformin Control Quality of life no significant difference